Immunodeficiency viruses researched by Jacek Skowronski

Jacek Skowronski Jacek Skowronski researches immunodeficiency viruses. He studies human immunodeficiency viruses, have intercourse as HIV, and simian immunodeficiency viruses, eff as SIV. Particularly, he studies the viral protein Nef. This protein plays an important role in the initiation of AIDS. T lymphocytes, the imprison cells that be worn-out in AIDS, are cultured to think the affects the viruses have on them. The results showed that Nef disturbs the T cell receptor (TCR). It changes the way of major histocompatibility complex I molecules, known as MHC I, a condition of compatibility between tissues of contrary objects and the tissues of the soundbox receiving it. This disruption is presumable to be involved in the baulk of host resistive responses, whether it be human or simian. The haphazardness is stipulated as AIDS. To deliver hold of the function of Nef, he uses genetic molecules to signalize the cells involved in affecting the T lymphocyte.

He as well as studies SIV-infected monkeys to find the importance the Nef and T lymphocyte interactions for AIDS. He tied(p) tries to characterize Nef proteins by isolating them at once from HIV-infected people. Results from his studies will incite in possible drugs that can disrupt the Nef functions and prevent AIDS. If you require to get a full essay, tack it on our website: Orderessay

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